S-adenosylmethionine or SAM-e may be the more natural way fight depression effectively. Depression is a mood disorder characterized by extreme feelings of sadness, helplessness, and hopelessness. Acute depression experienced for a certain period of time due to a death of a family member, separation, loss of career, and other possible reasons can be considered as normal. But when depression becomes chronic and it starts to affect the person's quality of life and his social relationships, it must be treated. Conventional treatment for depression includes several prescription medications with potentially harmful side effects. But if you want to reduce if not totally eliminate the side effects of anti-depressants, taking SAM-E supplements for depression is worth a try.
Alarmingly, more people are being diagnosed of clinical depression every day. In Europe, SAME supplement is being used to relieve the symptoms of depression and is considered an effective alternative to the anti-depressant Prozac. Some experts believe that SAM-E is also more effective than the herb St. John's Wort, known for its natural mood-enhancing and anti-depressive properties. SAME has also proven to provide relief in other conditions like arthritis, liver cirrhosis, cardiac diseases, and fibromyalgia.
SAM-E is a compound produced in the body from the mixture of methionine and adenosine triphosphate (ATP). It is not a vitamin or a mineral and it is neither an enzyme nor a hormone. SAM-E is a synthetic chemical used by the body to stimulate the synthesis of very important compounds including the DNA, cartilages and other connective tissues, melatonin hormone, and the neurotransmitters serotonin and dopamine. In healthy individuals, the liver produces adequate SAM-E levels. But it is highly dependent on the diet's folic acid and Vitamin B12 content. When the foods you eat are low in these vitamins, the body produces lesser SAM-E. Another factor that reduces the body's SAM-E levels is age, the older we get, the lesser SAM-E we have.
SAM-E for depression works by helping increase the levels of serotonin and dopamine in the brain. These neurotransmitters are responsible for controlling mood, behavior, and emotions. Clinical studies suggest that low levels of serotonin leads to depression. This is why the goal of depression treatment is to increase brain serotonin levels. SAM-E helps raise serotonin in the brain to boost mood and relieve all the negative feelings and other symptoms of depression.
The recommended daily dosage of SAM-E per day is 400-800 mg per day. SAM-E supplements are usually taken with folic acid, Vitamin B6, and B12. Those who have taken SAM-E for depression reported positive effects after two weeks of regular use. For maximum effects, SAM-E supplementation should take at least one month.
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